Although I have ambivalent feelings about the movie, lately I keep thinking about this quote from Crash:
In LA, nobody touches you. We're always behind this metal and glass. I think we miss that touch so much, that we crash into each other, just so we can feel something.
I think it carries over into the emotional realm too.
Like I was paraphrasing (from somewhere) to a friend the other day-- to be known intimately is both our deepest desire and greatest fear.